Zbynek Heger Selected Research

Sarcosine (Methylglycine)

11/2018	Post-treatment urinary sarcosine as a predictor of recurrent relapses in patients with prostate cancer.
3/2018	Differences in Urinary Amino Acid Patterns in Individuals with Different Types of Urological Tumor Urinary Amino Acid Patterns as Markers of Urological Tumors.
2/2018	Sarcosine influences apoptosis and growth of prostate cells via cell-type specific regulation of distinct sets of genes.
1/2018	Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma.
5/2017	Amino Acid Profiling of Zinc Resistant Prostate Cancer Cell Lines: Associations With Cancer Progression.
5/2016	Relation of exposure to amino acids involved in sarcosine metabolic pathway on behavior of non-tumor and malignant prostatic cell lines.
3/2016	Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer.
1/2016	Prostate tumor attenuation in the nu/nu murine model due to anti-sarcosine antibodies in folate-targeted liposomes.
1/2016	Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer.
3/2015	Paramagnetic nanoparticles as a platform for FRET-based sarcosine picomolar detection.

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Zbynek Heger Research Topics

Disease

26	Neoplasms (Cancer) 04/2022 - 01/2013
21	Prostatic Neoplasms (Prostate Cancer) 07/2022 - 07/2013
9	Neuroblastoma 01/2022 - 09/2017
5	Breast Neoplasms (Breast Cancer) 01/2021 - 05/2014
5	Carcinoma (Carcinomatosis) 03/2019 - 04/2014
3	Carcinogenesis 01/2020 - 12/2016
3	Melanoma (Melanoma, Malignant) 03/2019 - 01/2017
3	Hemolysis 01/2019 - 01/2017
3	Wounds and Injuries (Trauma) 10/2018 - 11/2015
2	Papilloma (Papillomatosis) 05/2022 - 12/2019
2	Virus Diseases (Viral Diseases) 05/2022 - 12/2019
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/2022 - 02/2017
2	Hypoxia (Hypoxemia) 01/2022 - 09/2017
2	Adenocarcinoma 11/2018 - 03/2015
2	Infections 01/2018 - 01/2017
2	Human Influenza (Influenza) 01/2016 - 10/2015
2	Cardiotoxicity 01/2016 - 10/2013
2	Heart Failure 01/2016 - 10/2013
1	Inflammation (Inflammations) 01/2022
1	Atherosclerosis 01/2022
1	Triple Negative Breast Neoplasms 01/2021
1	Drug-Related Side Effects and Adverse Reactions 10/2020
1	Communicable Diseases (Infectious Diseases) 01/2020
1	Bacterial Infections (Bacterial Infection) 10/2019
1	Pathologic Processes 03/2019
1	Neoplasm Metastasis (Metastasis) 02/2019
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 04/2018

Drug/Important Bio-Agent (IBA)

13	Sarcosine (Methylglycine)IBA 11/2018 - 07/2013
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2014
9	Biomarkers (Surrogate Marker)IBA 01/2020 - 07/2013
8	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 02/2014
7	Pharmaceutical PreparationsIBA 07/2022 - 10/2015
6	ZincIBA 01/2022 - 01/2016
6	Peptides (Polypeptides)IBA 07/2020 - 10/2015
6	MetallothioneinIBA 01/2020 - 06/2015
6	Amino Acids FDA Link 01/2019 - 04/2014
5	AntibodiesIBA 07/2022 - 01/2016
5	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 01/2016
4	Schiff Bases (Schiff Base)IBA 01/2022 - 01/2016
4	Protein Isoforms (Isoforms)IBA 01/2020 - 01/2016
4	IonsIBA 01/2019 - 01/2016
3	ApoferritinsIBA 07/2022 - 06/2016
3	novicidinIBA 01/2022 - 01/2016
3	ellipticineIBA 01/2021 - 02/2019
3	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2018 - 10/2013
3	Serine (L-Serine)FDA Link 05/2017 - 01/2016
3	Liposomes (Liposome)IBA 01/2017 - 02/2015
2	NucleotidesIBA 05/2022 - 12/2019
2	Etoposide (VP 16)FDA LinkGeneric 04/2022 - 02/2017
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022 - 01/2019
2	Cytostatic AgentsIBA 01/2021 - 02/2014
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021 - 01/2016
2	Biological ProductsIBA 01/2021 - 09/2017
2	ErbB Receptors (EGF Receptor)IBA 01/2021 - 09/2016
2	Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA 07/2020 - 04/2018
2	Antineoplastic Agents (Antineoplastics)IBA 02/2019 - 10/2013
2	AntigensIBA 11/2018 - 06/2016
2	EnzymesIBA 11/2018 - 01/2016
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 03/2018 - 01/2016
2	Glutamic Acid (Glutamate)FDA Link 03/2018 - 05/2016
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2018 - 01/2016
2	Carboplatin (JM8)FDA LinkGeneric 09/2017 - 02/2014
2	PlatinumIBA 09/2017 - 02/2014
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 09/2017 - 02/2014
2	Aspartic Acid (Aspartate)FDA Link 05/2017 - 05/2016
2	RNA (Ribonucleic Acid)IBA 01/2016 - 01/2016
2	Estrogen ReceptorsIBA 02/2015 - 05/2014
1	Colloids (Colloid)IBA 04/2022
1	CytokinesIBA 01/2022
1	CholesterolIBA 01/2022
1	Interleukin-10 (Interleukin 10)IBA 01/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022
1	Death Domain ReceptorsIBA 01/2022
1	LipidsIBA 01/2022
1	Stem Cell FactorIBA 01/2022
1	Interleukin-17 (Interleukin 17)IBA 01/2022
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2021
1	Hormones (Hormone)IBA 01/2021
1	Zinc Oxide FDA Link 01/2021
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 07/2020
1	Ferritins (Ferritin)IBA 07/2020
1	A-Form DNA (A-DNA)IBA 02/2019
1	Complement C3 (C3 Complement)IBA 01/2019
1	PoisonsIBA 01/2019
1	Protein CoronaIBA 01/2019
1	trioctyl phosphine oxide (TOPO)IBA 01/2019
1	GadoliniumIBA 10/2018
1	Blood Proteins (Serum Proteins)IBA 04/2018
1	Vorinostat FDA Link 04/2018

Therapy/Procedure

9	Therapeutics 01/2022 - 05/2014
4	Drug Therapy (Chemotherapy) 01/2021 - 10/2013
3	Quantum Dots (Quantum Dot) 05/2022 - 10/2018
3	Lasers (Laser) 01/2017 - 05/2014
2	Immunotherapy 01/2022 - 01/2022
2	Prostatectomy (Retropubic Prostatectomy) 11/2018 - 12/2015
2	Aftercare (After-Treatment) 06/2016 - 01/2016
1	Fat-Restricted Diet (Diet, Fat Restricted) 01/2022
1	Precision Medicine 01/2019
1	Transurethral Resection of Prostate (TURP) 11/2018